Full-Service Antibody Production Development Facility
Introduction to Antibody Production: The ability of the animal
immune system to produce antibodies that are capable of binding specifically to
antigens can be effectively harnessed to manufacture probes for the efficient
detection of molecules of interest in a variety of research and diagnostic
applications. For instance, rabbit is one of the most used species for antibody
production (such as rabbit anti-llama HRP). Rat, on the other hand, is used
less frequently because it does not offer more significant advantages (as
compared to a rabbit). But the general techniques for antibody production in
rats does not differ from those used in other species, such as rabbits.
Nearly all medical and cell
biology researchers make use of antibody technology in one form or another.
This ability of the animal immune systems to produce antibodies (such as goat anti-llama HRP which capable of binding specifically to
antigens) can be harnessed to manufacture probes for the detection of molecules
of interest in a variety of research and diagnostic applications. Certainly, no
other technology today allows researchers to design and manufacture such highly-specific
molecular recognition tools. Several important features (besides their high
specificity) make antibodies particularly conducive to the development of
probes. For example, except in those portions that determine antigen binding,
antibodies share a relatively uniform and well-characterized protein structure
that enables them to be purified, labeled, and detected, predictably and
reproducibly, by generalized methods.
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